ARV Facts

Facts about Antiretroviral Drugs

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Active substance: Nevirapine
Manufacturer: Boehringer-Ingelheim (Germany / USA)

Extract from the medication guide:

"VIRAMUNE is not a cure for HIV-1 infection; patients may continue to experience illnesses associated with advanced HIV-1 infection, including opportunistic infections. Patients should be advised to remain under the care of a physician when using VIRAMUNE."

Known side effects: more immune deficiency

“Patients developing signs or symptoms of severe skin reactions or hypersensitivity reactions (including, but not limited to, severe rash or rash accompanied by fever, general malaise, fatigue, muscle or joint aches, blisters, oral lesions, conjunctivitis, facial edema, and/or hepatitis, eosinophilia, granulocytopenia, lymphadenopathy, and renal dysfunction) must permanently discontinue VIRAMUNE and seek medical evaluation immediately”

Granulocytopenia = Low levels of granulocytes – a subtype of white blood cells (leucocytes) responsible for immune defence against infections – due to toxic effects of ARVs on blood cell formation in the bone marrow

The above has been extracted from the Viramune medication guide on the Boehringer-Ingelheim webpages.