ARV Facts

Facts about Antiretroviral Drugs

Find out more about
ARV damage to:

• Immune system
• Brain
• Heart
• Kidneys
• Liver
• Muscles
• Newborns
• DNA

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ARV organ damage

 

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ARV damage to the DNA

Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver.
Hepatology. 1999 Mar;29(3):985-7.
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Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations.
Environ Mol Mutagen. 2007 Apr-May;48(3-4):224-38.
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Relative mutagenic potencies of several nucleoside analogs, alone or in drug pairs, at the HPRT and TK loci of human TK6 lymphoblastoid cells.
Environ Mol Mutagen. 2007 Apr-May;48(3-4):239-47.
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