ARV Facts

Facts about Antiretroviral Drugs

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Adverse effects of antiretroviral therapy in HIV-1 infected children.
J Trop Pediatr. 2006 Aug;52(4):244-8
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Hepatotoxicity of antiretrovirals: incidence, mechanisms and management.
Drug Saf. 2005;28(1):53-66
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3'-Azido-3'-deoxythymidine (AZT) is a competitive inhibitor of thymidine phosphorylation in isolated rat heart and liver mitochondria.
Biochem Pharmacol. 2006 Jul 14;72(2):239-43.
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A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy syndrome.
AIDS. 2000 Feb 18;14(3):F25-32.
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Fatal portal hypertension, liver failure, and mitochondrial dysfunction after HIV-1 nucleoside analogue-induced hepatitis and lactic acidaemia.
Lancet. 2001 May 5;357(9266):1412-4.
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Hepatotoxicity of antiretroviral drugs.
Curr Pharm Des. 2005;11(28):3697-710. Review.
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